The significance of API integration in business platforms lies in its ability to connect disparate systems, allowing them to work cohesively. APIs (Application Programming Interfaces) enable secure data exchange between applications, automating workflows and enhancing efficiency. This integration allows businesses to leverage third-party services, enriching their offerings without building functionalities from scratch. APIs can facilitate real-time data sharing, improve user experiences by providing seamless interactions, and foster innovation by enabling developers to create new applications. Overall, API integration is essential for modern businesses aiming to remain competitive in an increasingly digital landscape.