The difference between asynchronous and synchronous communication in technology lies in the timing of information exchange. Synchronous communication requires all parties to be present and engaged simultaneously, such as in video conferencing or phone calls, where immediate feedback is essential. In contrast, asynchronous communication allows participants to exchange messages without being online at the same time, such as in email or forum discussions. This difference affects how information is processed and responded to, influencing collaboration efficiency, especially in remote or distributed work environments.