Cloud-native applications differ from traditional applications primarily in their architecture and deployment. Cloud-native apps are designed to take full advantage of cloud computing, enabling scalability, flexibility, and resilience. They are typically built using microservices, allowing for independent deployment and management of components. In contrast, traditional applications may be monolithic, making updates and scaling more challenging. Cloud-native applications also utilize containers and orchestration tools for efficient resource management. This approach promotes continuous integration and delivery, leading to faster development cycles and improved responsiveness to business needs.