Browsers interpret HTML, CSS, and JavaScript by rendering code into a visual representation of a webpage. When a user enters a URL, the browser requests the HTML document, which structures the content. CSS styles the visual elements, such as colors and layout, while JavaScript adds interactivity and dynamic functions. The browser's rendering engine processes these components in sequence to produce the final output displayed to the user. This interplay enables the creation of engaging and functional web experiences for users across different devices.