The significance of osmotic pressure in cells lies in its role in maintaining cell integrity and homeostasis. Osmotic pressure is the force exerted by the movement of water across a semi-permeable membrane due to differences in solute concentration. It regulates cell volume and ensures that nutrients and waste products are appropriately exchanged between the cell and its environment. Disruptions to osmotic pressure can lead to cell lysis or shrinkage, impacting cellular function and overall organism health.