The significance of bacterial resistance in antibiotic treatment is critical in the context of global health. Overuse and misuse of antibiotics have led to the emergence of antibiotic-resistant bacteria, making previously treatable infections increasingly difficult to manage. This resistance threatens the efficacy of standard treatments, leading to longer hospital stays, increased medical costs, and higher mortality rates. Addressing bacterial resistance requires a multifaceted approach, including responsible antibiotic usage, research into new treatments, and public education to prevent the spread of resistance.