A genetic disorder is an abnormal condition resulting from a malfunction in an organism’s genome. These disorders may arise from mutations in single genes (monogenic), or involve multiple genes (polygenic) and chromosomal abnormalities. They can lead to various health issues, including physical impairments, metabolic problems, and increased susceptibility to diseases. Genetic disorders can be inherited from one or both parents and can manifest at birth or later in life, significantly impacting an individual's quality of life and requiring medical intervention or management.