Challenges arising from the globalization of politics include the erosion of national sovereignty, increased interdependence, and the rise of complex global issues that transcend borders. These challenges require multilateral cooperation and compromise, complicating domestic governance as states balance global responsibilities with local needs. Furthermore, globalization can exacerbate inequalities, leading to social tensions and resistance against perceived external influences. Navigating these complexities demands innovative approaches to policy-making that account for diverse interests and promote sustainable development.