The story of the creation of man in Mesopotamian mythology revolves around the god Enki and the goddess Ninhursag. Enki created humans from clay to serve the gods, easing their burdens. In one version, they fashioned the first human from clay infused with the blood of a slain god, symbolizing the divine origin of humanity and its connection to the divine. This myth underscores themes of creation, divine purpose, and the relationship between gods and humans, highlighting the importance of humanity in maintaining the balance of the cosmos.