The mythological significance of the Garden of Eden in Judeo-Christian belief is profound. It represents the initial state of human existence, where Adam and Eve lived in harmony with God and nature, free from sin. The garden is often seen as a paradise, illustrating themes of innocence and temptation through the story of the forbidden fruit. The resulting banishment signifies the fall of man and the origin of sin, impacting the theological understanding of humanity's relationship with God.