In Greek mythology, the sorceress known for transforming Odysseus’ crew into animals is Circe. She resides on the island of Aea and uses her knowledge of magic and potions to enchant sailors. Odysseus, upon encountering her, is protected by the god Hermes, who provides him with an antidote to her spells. Circe's story is integral to themes of temptation, transformation, and the struggle for knowledge during Odysseus’ journey.