The prominent Native American leader who symbolized resistance against U.S. expansion was Tecumseh. He was a Shawnee chief who sought to unite various Native American tribes in the early 19th century to resist the encroachment of settlers on their lands. Tecumseh and his brother, Tenskwatawa (the Prophet), aimed to establish a confederation of tribes to reclaim their territory and halt American expansion. His efforts culminated in the formation of a multi-tribal alliance and active resistance during the War of 1812. Tecumseh's legacy is celebrated as a symbol of indigenous resistance and nationalism.