The famous artist and inventor of the Renaissance known for works like the Mona Lisa is Leonardo da Vinci. He was not only a painter but also a polymath who excelled in various disciplines, including science, engineering, anatomy, and sculpture. Da Vinci's artistic contributions are characterized by their detailed realism and innovative techniques, especially his use of sfumato and chiaroscuro. The Mona Lisa, with its enigmatic expression and masterful painting technique, is among the most celebrated works in art history. His legacy continues to influence artists and thinkers around the world.