The rebellion of the American colonists against Great Britain was led by notable figures such as George Washington, Samuel Adams, and Thomas Jefferson. This rebellion was primarily driven by growing dissatisfaction with British taxation without representation, restrictive trade policies, and lack of self-governance. The uprising culminated in the Declaration of Independence in 1776, where the colonies asserted their right to self-determination. The struggle for independence culminated in the Revolutionary War, ultimately resulting in the establishment of the United States of America and encouraging other movements for liberty and self-rule globally.