The empire established in the Americas during the Age of Exploration was the Spanish Empire. Initiated by Christopher Columbus’s voyages in the late 15th century, Spain rapidly expanded its territory throughout the Americas, claiming vast regions including modern-day Mexico, Central America, and large portions of South America. The Spanish Empire became known for its conquests, such as the fall of the Aztec and Inca empires, and for establishing a vast colonial administration. This empire brought significant cultural exchanges, including language, religion, and governance, while also having devastating effects on indigenous populations through disease, warfare, and exploitation.