Long-term high-calorie diets can lead to several detrimental health impacts, including obesity, heart disease, and type 2 diabetes. Excess caloric intake encourages weight gain, which can stress the body's systems and lead to conditions like hypertension and high cholesterol. Furthermore, high-calorie diets, particularly those rich in processed foods, may lack essential nutrients, contributing to malnutrition despite excess energy. Over time, these factors can severely impact quality of life and increase the likelihood of developing chronic diseases, necessitating awareness and dietary adjustments.