The significance of omega-6 fatty acids in the diet lies in their essential role in overall health. These fatty acids are crucial for cell membrane integrity, proper brain function, and hormone regulation. They also provide energy and are necessary for the synthesis of important compounds, such as eicosanoids, which are involved in inflammatory responses. However, a balanced intake with omega-3 fatty acids is important to maintain optimal health, as excessive omega-6 consumption can lead to inflammation and chronic disease.