Prolonged sitting negatively affects metabolic health by leading to a decline in insulin sensitivity and increasing the risk of developing conditions such as obesity and type 2 diabetes. Sedentary behavior can result in lower energy expenditure, contributing to weight gain and cardiovascular issues. Additionally, it has been associated with higher levels of triglycerides and cholesterol, ultimately impairing overall heart health. Regular movement throughout the day counteracts these effects, promoting a more active lifestyle that supports cardiovascular and metabolic function.