Leptin and ghrelin are two hormones that play crucial roles in appetite control. Leptin, produced by fat cells, signals fullness and helps regulate energy balance by inhibiting hunger. In contrast, ghrelin is known as the "hunger hormone" and is produced in the stomach; it stimulates appetite and promotes food intake. The interplay between these hormones helps maintain stable body weight. Disruptions in their levels can lead to overeating or weight gain, underscoring the need for balanced nutrition and regular physical activity to regulate their effects effectively.