While dietary supplements can be beneficial, potential side effects may occur, including gastrointestinal disturbances, allergic reactions, or interactions with medications. Overuse of certain supplements can lead to toxicity, particularly in fat-soluble vitamins like A, D, E, and K. Additionally, some supplements may not provide the promised benefits, potentially leading to ineffective health improvements. It's essential for individuals to consult healthcare professionals before starting any supplement regimen, ensuring safety, proper dosage, and screening for contraindications against existing health conditions.