A long-term sedentary lifestyle can lead to numerous adverse health outcomes, including obesity, cardiovascular disease, and type 2 diabetes. Lack of physical activity promotes muscle atrophy, decreases bone density, and negatively affects metabolism. Additionally, sedentary behavior is linked to poor mental health, increasing the risk of anxiety and depression. Over time, these effects can culminate in a lower quality of life and reduced lifespan, emphasizing the importance of regular physical activity for optimal health.