Long-term health effects of chronic inactivity can be severe. It significantly increases the risk of developing chronic conditions like obesity, type 2 diabetes, cardiovascular diseases, and certain cancers. Prolonged inactivity can also lead to muscle atrophy, decreased bone density, and poor mental health, including depression and anxiety. Additionally, inactive lifestyles can negatively affect mobility and overall quality of life as individuals age. To mitigate these risks, regular physical activity is essential for maintaining long-term health and well-being.