High-fructose corn syrup (HFCS) can negatively affect metabolism and contribute to various health issues. This sweetener, commonly found in processed foods and sugary beverages, is linked to increased fat accumulation, particularly around the abdomen. HFCS can lead to insulin resistance, promoting the risk of developing type 2 diabetes. Furthermore, excessive intake of HFCS can contribute to obesity, as it does not provide a feeling of fullness, leading individuals to consume more calories. Reducing HFCS intake is essential for maintaining healthy metabolic function and overall health.