During an hour of moderate cycling, individuals typically burn around 400-600 calories, depending on various factors such as intensity, weight, and metabolism. Cycling is an effective aerobic exercise that promotes cardiovascular fitness while also engaging lower body muscles. The calorie expenditure can vary significantly based on the individual's effort level; maintaining a steadier pace generally yields lower calorie burn compared to a more vigorous cycling session. Incorporating cycling into a fitness routine can provide substantial health benefits while being enjoyable.