During acclimatization to altitude, the body undergoes several physiological adjustments to cope with lower oxygen levels. Initially, breathing rate increases to enhance oxygen intake, and heart rate rises to improve blood circulation. Over time, the body begins to produce more red blood cells, enhancing oxygen delivery to tissues. Other adaptations include increased myoglobin production for oxygen storage in muscles and improved efficiency in energy production. These changes help prevent altitude sickness and allow for better performance in high-altitude conditions. Adequate hydration and gradual ascent are crucial for facilitating acclimatization.