The two continents connected by the Isthmus of Panama are North America and South America. This narrow strip of land serves as a crucial land bridge between the two continents and is historically significant for trade and migration. The Panama Canal, completed in 1914, is located within this isthmus, facilitating maritime trade by allowing ships to travel between the Atlantic and Pacific Oceans without navigating around South America. The isthmus is also rich in biodiversity and ecosystems, with numerous unique species found in the region. Its strategic location continues to have profound economic and environmental impacts.