The body of water located between Florida and Cuba is the Florida Straits. This narrow body of water connects the Gulf of Mexico to the Atlantic Ocean and plays a crucial role in marine navigation and trade. The straits serve as a migratory route for various marine species and support rich ecosystems. Additionally, the Florida Straits are historically significant, with events such as the Cuban Missile Crisis highlighting their geopolitical importance. The area is also a popular site for recreational activities, including fishing and boating.