The organ in the human body responsible for detoxifying substances is the liver. The liver plays a critical role in metabolizing nutrients, filtering blood, and eliminating toxins from the body. It processes medications, alcohol, and other harmful substances, converting them into less harmful compounds that can be excreted via bile or urine. Besides detoxification, the liver is essential for producing proteins, cholesterol, and various enzymes necessary for digestion. Its ability to regenerate makes it unique; even if significantly damaged, the liver can often recover and restore its function.