The body of water that separates Saudi Arabia and Africa is the Red Sea. This narrow sea runs along the western coast of Saudi Arabia and separates it from the northeastern coast of Africa, including countries like Egypt and Sudan. The Red Sea is known for its rich marine life and coral reefs, making it a popular destination for divers. Additionally, it serves as a significant maritime trade route, linking the Mediterranean Sea through the Suez Canal to the Indian Ocean, enhancing its economic and strategic importance in global shipping.