The organ in the human body responsible for detoxification is the "liver." The liver plays a vital role in metabolizing substances, filtering blood, and detoxifying harmful compounds such as drugs and alcohol. It converts toxins into less harmful substances that can be excreted through urine or bile. The liver also contributes to digestion by producing bile, which helps in fat digestion. Its ability to regenerate makes it unique, allowing it to recover from damage or disease over time.