The capital city of the Republic of Panama is Panama City. Located at the Pacific entrance of the Panama Canal, this vibrant metropolis serves as the political, administrative, and cultural center of the country. Panama City is known for its striking skyline, combining modern skyscrapers with historic colonial architecture. The city is also a significant financial and trading hub in Latin America, thanks to its strategic geographic location. Its rich history, diverse culture, and important role in global shipping make Panama City an essential part of the region's economy and heritage.