The central activity of the festival of San Gennaro in New York City is the feast and the procession honoring the patron saint of Naples, San Gennaro. The event features a variety of Italian foods, including sausage and peppers, zeppoles, and cannoli, emphasizing traditional cuisine. Festivities also include live music, games, and religious ceremonies, creating a vibrant atmosphere of celebration and community. This festival draws thousands of attendees, highlighting the Italian-American heritage and fostering a sense of cultural pride among participants and visitors alike.