Effective note-making during UPSC preparation includes strategies such as utilizing mind maps to visualize connections, employing bullet points for brevity, and integrating color coding for easy retrieval of information. It is important to categorize notes based on subjects and topics, emphasizing key concepts and definitions. Regularly reviewing and revising notes enhances retention. Additionally, combining digital tools with traditional methods can streamline the process, making notes easily accessible and editable, thus enriching the preparation journey.