Aspirants can prioritize topics for effective study in UPSC exams by using a strategic approach. First, they should analyze the syllabus and previous years' question papers to identify frequently tested subjects. Creating a study schedule based on topic weightage helps allocate time efficiently. Breaking down topics into sub-topics also assists in systematic learning. Utilizing tools like the Eisenhower Matrix can help distinguish between urgent and essential topics. Regularly reviewing and adjusting priorities based on progress ensures a focused study plan, optimizing preparation efforts for the exam.