Mary Eliza Mahoney is known for establishing the first children's hospital in America, significantly impacting pediatric care. Mahoney dedicated her life to nursing and was the first African American woman to graduate from a professional nursing school in the U.S. In addition to her groundbreaking achievements in nursing, she was an advocate for health equity and the advancement of minorities in the healthcare profession. Her efforts paved the way for future generations of nurses, particularly women of color, illustrating her profound influence on the field of healthcare and community service.