The notable actress known for her humanitarian work and activism is Audrey Hepburn. Beyond her acclaimed film career, Hepburn was a dedicated UNICEF Goodwill Ambassador, using her fame to advocate for children in need worldwide. She devoted herself to humanitarian causes, especially during her later years, addressing issues like hunger, poverty, and education. Hepburn's legacy as both an actress and activist continues to inspire, showcasing the power of celebrity to effect positive change.