The American writer known for the series "Little House on the Prairie" is Laura Ingalls Wilder. Based on her childhood experiences in the late 19th century, the series offers a glimpse into pioneer life on the American frontier. Wilder's storytelling blends historical realities with familial love and resilience. The books have become classics in American literature, illustrating the challenges and triumphs of a young girl growing up in a rapidly changing world, and they continue to resonate with readers today.