Edgar Allan Poe explored themes of guilt, madness, and death in his short stories. His works frequently delve into the human psyche, examining the struggle between reason and irrationality. The use of symbolism and mood creates an atmosphere of suspense and horror. In tales like "The Tell-Tale Heart," Poe illustrates the effects of paranoia and psychological torment. Additionally, themes of loss and the supernatural recur, reflecting existential questions about life and afterlife. His writings paved the way for modern psychological horror and gothic literature.