Georgia O'Keeffe's artistic career was significantly shaped by influences from her surroundings, especially the American Southwest. The vivid landscapes and natural elements of this region inspired her iconic floral paintings and striking desert scenes. O'Keeffe's unique use of color, form, and abstraction diverged from traditional representation, drawing attention to the beauty of nature. Additionally, her sense of independence and exploration of feminine identity in her art challenged societal norms of her time, making her a pivotal figure in modern art.