The prominent leader known for her role in the fight against apartheid in South Africa is Winnie Mandela. As an anti-apartheid activist and politician, she played a crucial part in the struggle for justice and equality. Her resilience in the face of imprisonment and harassment drew international attention to the injustices of apartheid. Winnie Mandela's work and sacrifices highlighted the broader struggle for freedom and human rights, making her an enduring symbol of resistance in South Africa. Despite facing controversies in her later years, her contributions remain significant in the history of the anti-apartheid movement.