Leonardo da Vinci's contributions to art and science are unparalleled, encompassing innovations in painting, anatomy, and engineering. As a painter, his masterpieces like "The Last Supper" and "Mona Lisa" showcase his mastery of perspective and chiaroscuro, influencing generations of artists. His scientific explorations, particularly in human anatomy, involved meticulous observations and dissections, leading to groundbreaking insights into physiology. Da Vinci's sketches of flying machines and other inventions underscore his visionary thinking, merging art with engineering. His multidisciplinary approach laid foundational principles for both the Renaissance and modern scientific inquiry, making him a quintessential polymath.