Artist Georgia O'Keeffe faced several challenges while gaining recognition in the male-dominated art world. Despite her innovative and influential work, she struggled with limited opportunities and the prevailing gender stereotypes of her time. O'Keeffe's distinctive style often went unappreciated initially, as critics and audiences were slow to recognize her contributions. Additionally, her marriage to fellow artist Alfred Stieglitz complicated her public persona, as he was often seen as the more prominent figure. However, she persisted and eventually gained acclaim, becoming an iconic figure in American modernism.