Cleopatra’s cultural heritage significantly affected her rule and political strategies. As the last Pharaoh of Ancient Egypt, she sought to preserve her kingdom's autonomy amidst Roman expansion. Her mixed lineage, including Macedonian Greek and Egyptian ancestry, allowed her to embody both Hellenistic and Egyptian cultures, which was crucial for gaining popular support. Cleopatra employed strategic alliances, such as her relationships with Julius Caesar and Mark Antony, to strengthen her position and assert Egypt’s power. Her multifaceted identity and political acumen made her an influential ruler in a tumultuous historical context.